voltage-gated potassium — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4497	Amifampridine	3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine	Others
	Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ...		Others
T11990	Meclofenamic acid	Meclofenamate	Others , Gap Junction Protein
	Meclofenamic acid (Meclofenamate) is a non-selective gap-junction blocker and a selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic acid has anti-inflammatory activities.		Others , Gap Junction Protein
T23497	UK 78282 hydrochloride		Potassium Channel
	UK 78282 hydrochloride, a novel potent and selective Kv1.3 blocker.UK 78282 hydrochloride inhibits Kv1.3 voltage-gated potassium channels and suppresses human T cell activation.		Potassium Channel
T12786	RY785		Potassium Channel
	RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.		Potassium Channel
T7502	PF 05089771 tosylate		Sodium Channel
	PF-05089771 is a voltage-gated sodium channel 1.7 (Nav1.7) blocker (IC50: 11, 16, 33, and 20 nM for 5N11S, 5A11L, 5A11S, and 5A11L Nav1.7 splice variants, respectively). It is selective for Nav1.7 over Nav1.1-1.6 and 1.8...		Sodium Channel
T1496	Amiodarone hydrochloride	Amiodar,Amiodarone HCl,Nexterone	Potassium Channel , Adrenergic Receptor , Autophagy
	Amiodarone hydrochloride (Amiodarone HCl) is an antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM C...		Potassium Channel , Adrenergic Receptor , Autophagy
T22925	Linopirdine dihydrochloride		Others
	KV7 (KCNQ) voltage-gated potassium channels blocker		Others
T16815	RY796		Others
	RY796 is an effective and selective inhibitor of voltage-gated potassium channel (IC50s: 0.25 μM and 0.09 μM for KV2.1 and KV2.2).		Others
T11787	Kv3 modulator 1		Others
	Kv3 modulator 1 is a promising compound for the treatment of inflammatory pain. As a modulator of Kv3 voltage-gated potassium channels, Kv3 modulator 1 exhibits potential therapeutic properties in this indication.		Others
T80064	Dendrotoxin-I	DTX-I	Potassium Channel
	Dendrotoxin-I, a neurotoxin from Dendroaspis snake venom, potently blocks K⁺ channels, specifically targeting voltage-gated potassium channel subunits KV1.1 and KV1.2 [1] [2] [3].		Potassium Channel
T63684	DAD dichloride
	DAD dichloride is an ion channel blocker that blocks voltage-gated potassium channels, a third-generation photoelectric switch that responds to visible light, and can be used to study visual function.
T27564	Hymenidin		5-HT Receptor
	Hymenidin, an alkaloid isolated from the Okinawan sponge Hymeniacidon sp. is a 5-hydroxytryptaminergic receptor antagonist and voltage-gated potassium channel inhibitor with potential antiprotozoal effects.It selectively...		5-HT Receptor
T80980	Tityustoxin-Kα	TsTx-Kα
	Tityustoxin-Kα (TsTx-Kα) acts as an inhibitor of potassium voltage-gated channels, exhibiting a dose-dependent blockade of the sustained outward current in cultured hippocampal neurons [1].
T62770	DAD
	DAD is an ion channel blocker (blocks voltage-gated potassium channels) and is a third generation photoelectric switch that responds to visible light.
T80497	KTX-Sp2		Potassium Channel
	KTX-Sp2, a potassium channel toxin, effectively blocks exogenous voltage-gated potassium channels Kv1.1, Kv1.2, and Kv1.3, as well inhibits the endogenous Kv1.3 channel and suppresses Ca2+ signaling in Jurkat T cells. Ad...		Potassium Channel
T75792	Huwentoxin XVI TFA
	Huwentoxin XVI TFA, a potent analgesic derived from the Chinese tarantula Ornithoctonus huwena, acts as a highly reversible and selective antagonist of mammalian N-type calcium channels (IC 50 of ~60 nM), with no impact ...
T80426	Jingzhaotoxin-IX		Sodium Channel
	Jingzhaotoxin-IX is a C-terminally amidated peptide neurotoxin consisting of 35 amino acid residues. It inhibits both tetrodotoxin-resistant and tetrodotoxin-sensitive isoforms of voltage-gated sodium channels, as well a...		Sodium Channel
T80851	VSTx-3	Kappa-TRTX-Gr4a,κ-Theraphotoxin-Gr4a,Voltage sensor toxin 3,Peptide F
	VSTx-3 is a potassium voltage-gated channel (K_V) blocker, which has also been shown to be a potent tetrodotoxin-sensitive (TTX-sensitive) sodium channel inhibitor, with particular efficacy against NaV1.8 channels, as ev...
T21819	Psora 4
	Psora-4 is a potent and selective inhibitor of K v 1.3 (voltage-gated potassium channels) with a Hill coefficient of 2 and an EC50 value of 3 nM [1]. Psora-4 has immunosuppressive activity and inhibits proliferation of h...
T80528	Ssm spooky toxin	SsTx Toxin	Potassium Channel
	Ssm Spooky Toxin, derived from Scolopendra mutilans, exhibits potent lethality affecting both hematological and respiratory systems primarily through the inhibition of KCNQ (voltage-gated potassium channel family 7) chan...		Potassium Channel